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PEPC(Phospho Ser15) Polyclonal Antibody, 100ul Cell Culture Plates Caspases exist as inactive proenzymes

SKU: 56986578333

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PEPC(Phospho Ser15) Polyclonal Antibody, 100ul Cell Culture Plates Caspases exist as inactive proenzymesThis gene encodes an aspartic proteinase that belongs to the peptidase family A1. The encoded protein is a digestive enzyme that is produced in the stomach and constitutes a major component of the gastric mucosa. This protein is also secreted into the serum. This protein is synthesized as an inactive zymogen that includes a highly basic prosegment. This enzyme is converted into its active mature form at low pH by sequential cleavage of the prosegment

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Description

Caspases exist as inactive proenzymes composed of a prodomain| a large protease subunit| and a small protease subunit

and the accumulation of insoluble dipeptide repeat protein aggregates that could be pathogenic in FTD-ALS patients (PMID: 23393093)

SYCP3 encodes an essential structural component of the synaptonemal complex

and interacts with several proteins involved in cytoskeletal organization

subcellular location:Shuttles between nucleus and cytoplasm

PEPC(Phospho Ser15) Polyclonal Antibody, 100ul Cell Culture Plates Caspases exist as inactive proenzymesThis gene encodes an aspartic proteinase that belongs to the peptidase family A1. The encoded protein is a digestive enzyme that is produced in the stomach and constitutes a major component of the gastric mucosa. This protein is also secreted into the serum. This protein is synthesized as an inactive zymogen that includes a highly basic prosegment. This enzyme is converted into its active mature form at low pH by sequential cleavage of the prosegment

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