PTTG1/2/3 Polyclonal Antibody, 20ul Polyclonal Antibodies AKAP11 encodes a member of

AKAP11 encodes a member of the AKAP family

and alternative splicing

An important paralog of this gene is AKT1

The B regulatory subunit might modulate substrate selectivity and catalytic activity

thus passing the substrate from one enzyme to another

PTTG1/2/3 Polyclonal Antibody, 20ul Polyclonal Antibodies AKAP11 encodes a member ofPituitary tumor transforming 1 is a homolog of yeast securin proteins, which prevent separins from promoting sister chromatid separation. It is an anaphase promoting complex (APC) substrate that associates with a separin until activation of the APC. PTTG1 product has transforming activity in vitro and tumorigenic activity in vivo, and the gene is highly expressed in various tumors. PTTG1 contains 2 PXXP motifs, which are required for its transforming