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GATA-3 Monoclonal Antibody, 50ul[BT-MCA0608] Nucleic Acid Amplification The splicing factor 3b subunit

SKU: 5656244369

4.3
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GATA-3 Monoclonal Antibody, 50ul[BT-MCA0608] Nucleic Acid Amplification The splicing factor 3b subunitThis gene encodes a protein which belongs to the GATA family of transcription factors. The protein contains two GATA type zinc fingers and is an important regulator of T cell development and plays an important role in endothelial cell biology. Defects in this gene are the cause of hypoparathyroidism with sensorineural deafness and renal dysplasia.

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Description

The splicing factor 3b subunit 4 encoded by SF3B4 cross-links to a region in the pre-mRNA immediately upstream of the branchpoint sequence in pre-mRNA in the prespliceosomal complex A

but not rodents

The protein encoded by AURKA is a cell cycle-regulated kinase that appears to be involved in microtubule formation and/or stabilization at the spindle pole during chromosome segregation

together with splicing factor 3a and a 12S RNA unit

Transcript variants with alternative splicing in the 5' UTR have been found for this gene

GATA-3 Monoclonal Antibody, 50ul[BT-MCA0608] Nucleic Acid Amplification The splicing factor 3b subunitThis gene encodes a protein which belongs to the GATA family of transcription factors. The protein contains two GATA type zinc fingers and is an important regulator of T cell development and plays an important role in endothelial cell biology. Defects in this gene are the cause of hypoparathyroidism with sensorineural deafness and renal dysplasia.

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