TRAP240 Polyclonal Antibody, 50ul[BT-AP09182] Peripheral Blood Separation Tube a leukocyte-specific adaptor protein important

a leukocyte-specific adaptor protein important for immune cell signaling

contains two regions of tandem immunoglobulin domains on either side of a PEVK region that is rich in proline

PTM:Phosphorylated on tyrosine residues upon TCR or BCR activation

This protein may be involved in completion and maintenance of the myelin sheath and in cell-cell communication

indicating a potential role in transcriptional regulation

TRAP240 Polyclonal Antibody, 50ul[BT-AP09182] Peripheral Blood Separation Tube a leukocyte-specific adaptor protein importantMED13 (mediator complex subunit 13) encodes a component of the mediator complex (also known as TRAP, SMCC, DRIP, or ARC), a transcriptional coactivator complex thought to be required for the expression of almost all genes. The mediator complex is recruited by transcriptional activators or nuclear receptors to induce gene expression, possibly by interacting with RNA polymerase II and promoting the formation of a transcriptional pre initiation complex.