HMX2 Polyclonal Antibody, 50ul Cellular Function Assays Mutations in this gene are

Mutations in this gene are associated with a variety of human cancers

a severe combined immunodeficiency disease characterized by a selective absence of CD8-positive T-cells

and chromatin remodeling

An important paralog of this gene is GPR137B

a fourth conserved transmembrane domain

HMX2 Polyclonal Antibody, 50ul Cellular Function Assays Mutations in this gene areThe protein encoded by this gene is a member of the NKL homeobox family of transcription factors. Members in this family are of ancient origin and play an important role in organ development during embryogenesis. A related mouse protein plays a role in patterning of inner ear structures. In humans, variations in a region containing this gene have been associated with inner ear malformations, vestibular dysfunction, and hearing loss.