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TRPC1 Polyclonal Antibody, 100ul Thermal Control A full-length representative protein consists

SKU: 5612919516

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TRPC1 Polyclonal Antibody, 100ul Thermal Control A full-length representative protein consistsThe protein encoded by this gene is a membrane protein that can form a non selective channel permeable to calcium and other cations. The encoded protein appears to be induced to form channels by a receptor tyrosine kinase activated phosphatidylinositol second messenger system and also by depletion of intracellular calcium stores. Two transcript variants encoding different isoforms have been found for this gene.

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Description

A full-length representative protein consists of an extracellular region| composed of three immunoglobulin-like domains| a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain

It has been shown to interact with TRAF family members

this process is critical for Na(+) reabsorption at the tubules (PubMed: 24561201)

which are involved in patterning and differentiation of various tissue types

which suggested its role in the TGF beta induced growth inhibition

TRPC1 Polyclonal Antibody, 100ul Thermal Control A full-length representative protein consistsThe protein encoded by this gene is a membrane protein that can form a non selective channel permeable to calcium and other cations. The encoded protein appears to be induced to form channels by a receptor tyrosine kinase activated phosphatidylinositol second messenger system and also by depletion of intracellular calcium stores. Two transcript variants encoding different isoforms have been found for this gene.

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