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XDH Polyclonal Antibody, 20ul DNA/RNA Isolation & Purification The encoded protein interacts with

SKU: 56045622200

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XDH Polyclonal Antibody, 20ul DNA/RNA Isolation & Purification The encoded protein interacts withXanthine dehydrogenase belongs to the group of molybdenum containing hydroxylases involved in the oxidative metabolism of purines. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. Xanthine dehydrogenase can be converted to xanthine oxidase by reversible sulfhydryl oxidation or by irreversible proteolytic modification. Defects in xanthine dehydrogenase cause

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Description

The encoded protein interacts with these substrates via a histidine triad motif

Promotes anchorage-independent growth of immortalized melanocytes and astrocytes which is a key component in tumor cell expansion

Defects in this gene are a cause of severe combined immunodeficiency autosomal recessive T-cell-negative/B-cell-positive/NK-cell-positive (SCIDBNK)

Mutations in GATA4 have been associated with cardiac septal defects

subsequent to hypoxia-dependent phosphorylation of Ser-122

XDH Polyclonal Antibody, 20ul DNA/RNA Isolation & Purification The encoded protein interacts withXanthine dehydrogenase belongs to the group of molybdenum containing hydroxylases involved in the oxidative metabolism of purines. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. Xanthine dehydrogenase can be converted to xanthine oxidase by reversible sulfhydryl oxidation or by irreversible proteolytic modification. Defects in xanthine dehydrogenase cause

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