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IL23R Polyclonal Antibody, 20ul Pipette Controller Mutations in NME1 have been

SKU: 55952458221

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IL23R Polyclonal Antibody, 20ul Pipette Controller Mutations in NME1 have beenThe protein encoded by this gene is a subunit of the receptor for IL23A IL23. This protein pairs with the receptor molecule IL12RB1 IL12Rbeta1, and both are required for IL23A signaling. This protein associates constitutively with Janus kinase 2 (JAK2), and also binds to transcription activator STAT3 in a ligand dependent manner.

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Description

Mutations in NME1 have been identified in aggressive neuroblastomas

Axon repulsion in growth cones may be caused by its association with DCC that may trigger signaling for repulsion

This protein may play a role in development of the nervous system

MED14 is known to escape chromosome X-inactivation

Expressed in various cancer cell lines

IL23R Polyclonal Antibody, 20ul Pipette Controller Mutations in NME1 have beenThe protein encoded by this gene is a subunit of the receptor for IL23A IL23. This protein pairs with the receptor molecule IL12RB1 IL12Rbeta1, and both are required for IL23A signaling. This protein associates constitutively with Janus kinase 2 (JAK2), and also binds to transcription activator STAT3 in a ligand dependent manner.

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