RAD9(Phospho Ser272) Rabbit Polyclonal Antibody, 100ul Low retention tips Phosphorylation by protein kinase C

Phosphorylation by protein kinase C or binding to calcium-calmodulin inhibits its association with actin and with the plasma membrane| leading to its presence in the cytoplasm

MIM 601912) is required for many cellular processes

Polymorphisms in this gene may be associated with susceptibility for migraine headaches

This transmembrane protein localizes to the endoplasmic reticulum of many tissues

is activated by endoplasmic reticulum stress

RAD9(Phospho Ser272) Rabbit Polyclonal Antibody, 100ul Low retention tips Phosphorylation by protein kinase CCatalytic activity: Exonucleolytic cleavage in the 3' to 5' direction to yield nucleoside 5' phosphates. Component of the 9 1 1 cell cycle checkpoint response complex that plays a major role in DNA repair. The 9 1 1 complex is recruited to DNA lesion upon damage by the RAD17 replication factor C (RFC) clamp loader complex. Acts then as a sliding clamp platform on DNA for several proteins involved in long patch base excision repair (LP BER). The 9 1 1