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PP2CEpsilon Polyclonal Antibody, 50ul Gloves Mutations in this gene are

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PP2CEpsilon Polyclonal Antibody, 50ul Gloves Mutations in this gene areProtein phosphatase 1L encoded by PPM1L is a magnesium or manganese requiring phosphatase that is involved in several signaling pathways. The encoded protein downregulates apoptosis signal regulating kinase 1, a protein that initiates a signaling cascade that leads to apoptosis when cells are subjected to cytotoxic stresses. This protein also is an endoplasmic reticulum transmembrane protein that helps regulate ceramide transport from the endoplasmic

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Description

Mutations in this gene are also associated with hyperphosphatemic familial tumoral calcinosis (HFTC)

A pseudogene has been identified on chromosome 21

This gene encodes a member of the inwardly rectifying potassium channel family of proteins

The predicted protein is proline-rich and contains several dopamine D4 receptor signatures and PRINTS domains

The protein contains the signature active site residues of the cysteine protease papain superfamily

PP2CEpsilon Polyclonal Antibody, 50ul Gloves Mutations in this gene areProtein phosphatase 1L encoded by PPM1L is a magnesium or manganese requiring phosphatase that is involved in several signaling pathways. The encoded protein downregulates apoptosis signal regulating kinase 1, a protein that initiates a signaling cascade that leads to apoptosis when cells are subjected to cytotoxic stresses. This protein also is an endoplasmic reticulum transmembrane protein that helps regulate ceramide transport from the endoplasmic

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