Sp3/4 Polyclonal Antibody, 100ul Enzyme-Linked Immunosorbent Assay (ELISA) Mutations in CNNM2 are associated

Mutations in CNNM2 are associated with renal hypomagnesemia

as with the oncogenic PLZF-RAR chimera of promyelocytic leukemias

GO annotations related to this gene include chromatin binding

and thereby protect cells against oxidative damage

Overexpression of this gene is associated with increased differentiation and proliferation in colorectal cancer

Sp3/4 Polyclonal Antibody, 100ul Enzyme-Linked Immunosorbent Assay (ELISA) Mutations in CNNM2 are associatedSP3 (Sp3 transcription factor) belongs to a family of Sp1 related genes that encode transcription factors that regulate transcription by binding to consensus GC and GT box regulatory elements in target genes. This protein contains a zinc finger DNA binding domain and several transactivation domains, and has been reported to function as a bifunctional transcription factor that either stimulates or represses the transcription of numerous genes.