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p73 (Acetyl Lys327) Polyclonal Antibody, 100ul Transporters Multiple transcript variants encoding the

SKU: 5390450944

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p73 (Acetyl Lys327) Polyclonal Antibody, 100ul Transporters Multiple transcript variants encoding theTP73 encodes a member of the p53 family of transcription factors involved in cellular responses to stress and development. It maps to a region on chromosome 1p36 that is frequently deleted in neuroblastoma and other tumors, and thought to contain multiple tumor suppressor genes. The demonstration that TP73 is monoallelically expressed (likely from the maternal allele), supports the notion that it is a candidate gene for neuroblastoma. Many transcript

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Description

Multiple transcript variants encoding the same protein have been identified for this gene

This gene is highly conserved in most organisms

Leptin receptor encoded by LEPR belongs to the gp130 family of cytokine receptors that are known to stimulate gene transcription via activation of cytosolic STAT proteins

which also associates with the herpes simplex virus (HSV) protein VP16 that induces transcription of HSV immediate-early genes

There is a DQHA (X)2E (X)4E motif found at the C-terminus of the protein encoded by this gene that forms part of the active site of the nuclease

p73 (Acetyl Lys327) Polyclonal Antibody, 100ul Transporters Multiple transcript variants encoding theTP73 encodes a member of the p53 family of transcription factors involved in cellular responses to stress and development. It maps to a region on chromosome 1p36 that is frequently deleted in neuroblastoma and other tumors, and thought to contain multiple tumor suppressor genes. The demonstration that TP73 is monoallelically expressed (likely from the maternal allele), supports the notion that it is a candidate gene for neuroblastoma. Many transcript

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