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LPIN1 Polyclonal Antibody, 50ul In vitro Transcription inhibits VAV1 activation upon TCR

SKU: 53835381378

4.5
USD162.00 USD192.00

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LPIN1 Polyclonal Antibody, 50ul In vitro Transcription inhibits VAV1 activation upon TCRThis gene encodes a magnesium ion dependent phosphatidic acid phosphohydrolase enzyme that catalyzes the penultimate step in triglyceride synthesis including the dephosphorylation of phosphatidic acid to yield diacylglycerol. Expression of this gene is required for adipocyte differentiation and it also functions as a nuclear transcriptional coactivator with some peroxisome proliferator activated receptors to modulate expression of other genes involved

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Description

inhibits VAV1 activation upon TCR engagement and imposes a requirement for CD28 costimulation for proliferation and IL-2 production

The correlation of anti-sperm antibodies with cases of unexplained infertility implicates a role for these antibodies in blocking fertilization

It is crucial for several signalling pathways by controlling the S-glutathionylation status of signalling mediators

they have different patterns of tissue-specific expression and thus may play different physiologic roles

High degree of protection against acids

LPIN1 Polyclonal Antibody, 50ul In vitro Transcription inhibits VAV1 activation upon TCRThis gene encodes a magnesium ion dependent phosphatidic acid phosphohydrolase enzyme that catalyzes the penultimate step in triglyceride synthesis including the dephosphorylation of phosphatidic acid to yield diacylglycerol. Expression of this gene is required for adipocyte differentiation and it also functions as a nuclear transcriptional coactivator with some peroxisome proliferator activated receptors to modulate expression of other genes involved

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