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GNAS3 Polyclonal Antibody, 20ul Micro Centrifuge Tubes cyclins A through H

SKU: 52535323741

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GNAS3 Polyclonal Antibody, 20ul Micro Centrifuge Tubes cyclins A through HThis locus has a highly complex imprinted expression pattern. It gives rise to maternally, paternally, and biallelically expressed transcripts that are derived from four alternative promoters and 5' exons. Some transcripts contain a differentially methylated region (DMR) at their 5' exons, and this DMR is commonly found in imprinted genes and correlates with transcript expression. An antisense transcript is produced from an overlapping locus on the

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Description

cyclins A through H

and is found to be upregulated in multiple cancer cell lines

Mutations or defects in the gene encoding CEP55 result in a failure to exit mitosis and may be associated with tumor progression

This complex is necessary for proper chromosome segregation and completion of cytokinesis

Mutations within PAX2 have been shown to result in optic nerve colobomas and renal hypoplasia

GNAS3 Polyclonal Antibody, 20ul Micro Centrifuge Tubes cyclins A through HThis locus has a highly complex imprinted expression pattern. It gives rise to maternally, paternally, and biallelically expressed transcripts that are derived from four alternative promoters and 5' exons. Some transcripts contain a differentially methylated region (DMR) at their 5' exons, and this DMR is commonly found in imprinted genes and correlates with transcript expression. An antisense transcript is produced from an overlapping locus on the

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