CLC1A Polyclonal Antibody, 50ul In vitro Assessment The encoded protein is a

The encoded protein is a component of the phosphatidylinositol-3-kinase (PI3K) complex which mediates vesicle-trafficking processes

Mutations in this gene are associated with autosomal recessive spastic paraplegia-15

This protein is initially found in the cytoplasm but is translocated into the nucleus upon phosphorylation

whereas other family members encode isoforms that predominate in muscle (M) and liver (L) cells

The encoded protein may function as a positive regulator in the T-cell receptor signaling pathway

CLC1A Polyclonal Antibody, 50ul In vitro Assessment The encoded protein is aThis gene encodes a member of the C type lectin C type lectin like domain (CTL CTLD) superfamily. Members of this family share a common protein fold and have diverse functions, such as cell adhesion, cell cell signaling, glycoprotein turnover, and roles in inflammation and immune response. The encoded protein may play a role in regulating dendritic cell function. This gene is closely linked to other CTL CTLD superfamily members on chromosome 12p13 in