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MeCP2 Polyclonal Antibody, 50ul Sealing Film Multiple transcript variants encoding different

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MeCP2 Polyclonal Antibody, 50ul Sealing Film Multiple transcript variants encoding differentDNA methylation is the major modification of eukaryotic genomes and plays an essential role in mammalian development. Human proteins MECP2, MBD1, MBD2, MBD3, and MBD4 comprise a family of nuclear proteins related by the presence in each of a methyl CpG binding domain (MBD). Each of these proteins, with the exception of MBD3, is capable of binding specifically to methylated DNA. MECP2, MBD1 and MBD2 can also repress transcription from methylated gene

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Description

Multiple transcript variants encoding different isoforms have been found for NFYC

Deletion of this gene has been associated with myelodysplastic syndrome and acute myelogenous leukemia

YWHAH contains a 7 bp repeat sequence in its 5' UTR

Nucleoside-triphosphatase

This gene has been found to be mutated or translocated in many cancers including acute myeloid leukaemia| and expansion of CGG repeats in the 5' UTR has been associated with Jacobsen syndrome

MeCP2 Polyclonal Antibody, 50ul Sealing Film Multiple transcript variants encoding differentDNA methylation is the major modification of eukaryotic genomes and plays an essential role in mammalian development. Human proteins MECP2, MBD1, MBD2, MBD3, and MBD4 comprise a family of nuclear proteins related by the presence in each of a methyl CpG binding domain (MBD). Each of these proteins, with the exception of MBD3, is capable of binding specifically to methylated DNA. MECP2, MBD1 and MBD2 can also repress transcription from methylated gene

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