FBX46 Rabbit Polyclonal Antibody, 20ul Bacterial Expression Spectrin alpha chain non-erythrocytic 1

Spectrin alpha chain non-erythrocytic 1 has been implicated in other cellular functions including DNA repair and cell cycle regulation

creating unbranched filaments

DNA mismatch repair protein Msh6 heterodimerizes with MSH2 to form a mismatch recognition complex that functions as a bidirectional molecular switch that exchanges ADP and ATP as DNA mismatches are bound and dissociated

Key genes for eye color and hair color also map to chromosome 19

Additional transcript variants have been describe

FBX46 Rabbit Polyclonal Antibody, 20ul Bacterial Expression Spectrin alpha chain non-erythrocytic 1Members of the F box protein family such as FBXO46 are characterized by an approximately 40 amino acid F box motif. SCF complexes formed by SKP1 (MIM 601434) cullin (see CUL1; MIM 603134) and F box proteins act as protein ubiquitin ligases. F box proteins interact with SKP1 through the F box and they interact with ubiquitination targets through other protein interaction domains (Jin et al. 2004