P53 Polyclonal Antibody, 50ul[BT-AP06811] Gel & Buffers In the developing urogenital system

In the developing urogenital system

The protein has antibacterial and antifungal antimicrobial activity

which is located 10 kb downstream from this gene

The encoded kinase participates in the regulation of vascular endothelial growth factor (VEGF) expression

Mice lacking this gene are also hypersensitive to interferon| suggesting a function of this protein in downregulating interferon responses| independent of its isopeptidase activity towards ISG15

P53 Polyclonal Antibody, 50ul[BT-AP06811] Gel & Buffers In the developing urogenital systemTP53 (tumor protein p53) encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in TP53 are associated with a variety of human cancers, including hereditary cancers such as Li Fraumeni