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CD6 Polyclonal Antibody, 100ul[BT-AP01538] Diagnostic Probes & Oligos This gene encodes a member

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CD6 Polyclonal Antibody, 100ul[BT-AP01538] Diagnostic Probes & Oligos This gene encodes a memberCD5 has been identified as a transmembrane glycoprotein that is expressed on 70% of normal peripheral blood lymphocytes and on virtually all T lymphocytes in thymus and peripheral blood. Activation of T cells through the T cell receptor (TCR) results in tyrosine phosphorylation of CD5, and the absence of CD5 renders T cells hyper responsive to TCR mediated activation. CD5 associates with the TCR CD3 chain, and with the Src family kinase, Lck p56. The

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Description

This gene encodes a member of the chromodomain helicase DNA-binding protein family

including ankyrin repeats

Mutations in DCLRE1C can cause Athabascan-type severe combined immunodeficiency (SCIDA) and Omenn syndrome

8 kb region that may be amplified

The function of this gene has not yet been defined

CD6 Polyclonal Antibody, 100ul[BT-AP01538] Diagnostic Probes & Oligos This gene encodes a memberCD5 has been identified as a transmembrane glycoprotein that is expressed on 70% of normal peripheral blood lymphocytes and on virtually all T lymphocytes in thymus and peripheral blood. Activation of T cells through the T cell receptor (TCR) results in tyrosine phosphorylation of CD5, and the absence of CD5 renders T cells hyper responsive to TCR mediated activation. CD5 associates with the TCR CD3 chain, and with the Src family kinase, Lck p56. The

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