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Fhit Polyclonal Antibody, 100ul[BT-AP03231] Pathway and Network Analysis It is localized to the

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Fhit Polyclonal Antibody, 100ul[BT-AP03231] Pathway and Network Analysis It is localized to theFHIT, a member of the histidine triad gene family, encodes a diadenosine 5',5''' P1,P3 triphosphate hydrolase involved in purine metabolism. The gene encompasses the common fragile site FRA3B on chromosome 3, where carcinogen induced damage can lead to translocations and aberrant transcripts of this gene. In fact, aberrant transcripts from this gene have been found in about half of all esophageal, stomach, and colon carcinomas. Alternatively spliced

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Description

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Fhit Polyclonal Antibody, 100ul[BT-AP03231] Pathway and Network Analysis It is localized to theFHIT, a member of the histidine triad gene family, encodes a diadenosine 5',5''' P1,P3 triphosphate hydrolase involved in purine metabolism. The gene encompasses the common fragile site FRA3B on chromosome 3, where carcinogen induced damage can lead to translocations and aberrant transcripts of this gene. In fact, aberrant transcripts from this gene have been found in about half of all esophageal, stomach, and colon carcinomas. Alternatively spliced

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