CENPQ Polyclonal Antibody, 50ul Microbial Genome Editing USP17 subfamily

USP17 subfamily

The protein binds to the SH3 domains of several proteins including the ABL1 and SYK protein tyrosine kinases | and functions as a cytoplasmic adaptor protein to positively regulate transcriptional activity in T| natural killer (NK)| and basophilic cells

are associated with spinal muscular atrophy| mutations in the centromeric copy do not lead to disease

and has been shown to bind CDC42 in the presence of GTP

and has higher inhibitory activity when phosphorylated

CENPQ Polyclonal Antibody, 50ul Microbial Genome Editing USP17 subfamilyCENPQ is a subunit of a CENPH (MIM 605607) CENPI (MIM 300065) associated centromeric complex that targets CENPA (MIM 117139) to centromeres and is required for proper kinetochore function and mitotic progression (Okada et al., 2006