Csk Monoclonal Antibody, 100ul Antibody Development PHLDB2 and RSN

PHLDB2 and RSN

Polyglutamine repeat expansion in the AR is linked to Kennedy's disease (X-linked spinal and bulbar muscular atrophy)

Directly associates with HAX1

The specific function of this protein has not yet been determined| although it is thought to be a tumor suppressor

Members of this family function as water-permeable channels in the epithelia of organs that absorb and excrete water

Csk Monoclonal Antibody, 100ul Antibody Development PHLDB2 and RSNcatalytic activity: ATP + a [protein] L tyrosine = ADP + a [protein] L tyrosine phosphate.,function: Specifically phosphorylates 'Tyr 504' on LCK, which acts as a negative regulatory site. Can also act on the LYN and FYN kinases.,PTM: Autophosphorylation of Tyr 304 occurs only at abnormally high CSK concentrations in vitro.,similarity: Belongs to the protein kinase superfamily. Tyr protein kinase family.,similarity: Belongs to the protein kinase