STAC3 Polyclonal Antibody, 20ul Molecular Biology Multiple alternatively spliced transcript variants

Multiple alternatively spliced transcript variants that encode distinct isoforms have been reported for MAP2K3

This gene encodes a single-pass type II membrane protein that is a member of the peptidase S9B family of serine proteases

thereby influencing alternative transcript splicing

at least one of which encodes a preproprotein that is proteolytically processed to generate the heavy chain of the inter-alpha-trypsin inhibitor complex

Mutations in this gene are a cause of Cushing disease and adrenocortical hyperplasia

STAC3 Polyclonal Antibody, 20ul Molecular Biology Multiple alternatively spliced transcript variantsThe protein encoded by this gene is a component of the excitation contraction coupling machinery of muscles. This protein is a member of the Stac gene family and contains an N terminal cysteine rich domain and two SH3 domains. Mutations in this gene are a cause of Native American myopathy.