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The encoded protein is found as a homodimer and is a member of the syndecan proteoglycan family

This gene encodes a major histocompatibility complex (MHC) class I-related molecule that binds to the NKG2D receptor on natural killer (NK) cells to trigger release of multiple cytokines and chemokines that in turn contribute to the recruitment and activation of NK cells

Multiple transcript variants encoding different isoforms have been found for ARHGAP22

characterized by severe proteinuria and loss of the slit diaphragm and foot processes

CBLB Polyclonal Antibody, 50ul Glassware Sets Get ready for accurate andThe N terminus is composed of the phosphotyrosine binding (PTB) domain, a short linker region and the RING type zinc finger. The PTB domain, which is also called TKB (tyrosine kinase binding) domain, is composed of three different subdomains: a four helix bundle (4H), a calcium binding EF hand and a divergent SH2 domain.,The RING type zinc finger domain mediates binding to an E2 ubiquitin conjugating enzyme.,The UBA domain interacts with poly