DNA-PKCS Polyclonal Antibody, 100ul[BT-AP02677] Cell Culture Dishes The dual specificity phosphatase 4

The dual specificity phosphatase 4 encoded by DUSP4 is a member of the dual specificity protein phosphatase subfamily

This protein localizes to the endoplasmic reticulum and is known to metabolize as many as 25% of commonly prescribed drugs

thereby regulating imprinted expression

The encoded protein interacts with histone deacetylases and functions as a repressor of polymerase II transcription

Additional isoforms resulting from the use of alternate in-frame translation initiation codons have also been described

DNA-PKCS Polyclonal Antibody, 100ul[BT-AP02677] Cell Culture Dishes The dual specificity phosphatase 4PRKDC (protein kinase, DNA activated, catalytic polypeptide) encodes the catalytic subunit of the DNA dependent protein kinase (DNA PK). It functions with the Ku70 Ku80 heterodimer protein in DNA double strand break repair and recombination. The protein encoded is a member of the PI3 PI4 kinase family.