SNX4 Polyclonal Antibody, 50ul Long RNA Synthesis Alternative splicing has been observed

Alternative splicing has been observed at this locus and four transcript variants

When activated| the encoded protein is known to inhibit CDC25C phosphatase| preventing entry into mitosis| and has been shown to stabilize the tumor suppressor protein p53| leading to cell cycle arrest in G1

|The C1 domain| containing the phorbol ester/DAG-type region 1 (C1A) and 2 (C1B)| is the diacylglycerol sensor and the C2 domain is a non-calcium binding domain

Naturally occuring read-through transcripts

Translocation t(1

SNX4 Polyclonal Antibody, 50ul Long RNA Synthesis Alternative splicing has been observedSNX4 (sorting nexin 4) encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. This protein associated with the long isoform of the leptin receptor and with receptor tyrosine kinases for platelet derived growth factor, insulin, and epidermal growth factor in cell cultures, but its function is unknown. This protein may