Chk2(Phospho Ser516) Polyclonal Antibody, 50ul Lysosome ZIC1 encodes a transcription factor

ZIC1 encodes a transcription factor that can bind and transactivate the apolipoprotein E gene

The encoded protein is a member of the MCM family of chromatin-binding proteins and can interact with at least two other members of this family

Alternative transcript variants encoding distinct isoforms have been described

This protein localizes to the nucleus and the cytoplasm

TPO-R deficient mice were severely thrombocytopenic

Chk2(Phospho Ser516) Polyclonal Antibody, 50ul Lysosome ZIC1 encodes a transcription factorIn response to DNA damage and replication blocks, cell cycle progression is halted through the control of critical cell cycle regulators. The protein encoded by this gene is a cell cycle checkpoint regulator and putative tumor suppressor. It contains a forkhead associated protein interaction domain essential for activation in response to DNA damage and is rapidly phosphorylated in response to replication blocks and DNA damage. When activated, the