GLI-1 Polyclonal Antibody, 100ul Peptide Library This protein has been shown

This protein has been shown to interact with| and inhibit the activity of| TRPS1| a transcription suppressor of GATA-mediated transcription

The BimEL and BimL isoforms may be sequestered to the dynein motor complex through an interaction with the dynein light chain and released from this complex during apoptosis

This gene is the inferred homolog of the Saccharomyces cerevisiae carboxymethyltransferase gene PPM2 that is essential for the synthesis of the hypermodified guanosine Wybutosine (yW)

transferring phosphorus-containing groups and protein tyrosine kinase activity

Increased expression of this gene leads to translocation of the encoded protein to the cell membrane

GLI-1 Polyclonal Antibody, 100ul Peptide Library This protein has been shownThis gene encodes a member of the Kruppel family of zinc finger proteins. The encoded transcription factor is activated by the sonic hedgehog signal transduction cascade and regulates stem cell proliferation. The activity and nuclear localization of this protein is negatively regulated by p53 in an inhibitory loop. Multiple transcript variants encoding different isoforms have been found for this gene.