Human Semaphorin 6D, SEMA6D ELISA Kit, 96T Cell fragmentation and collection AVEN is highly expressed in

AVEN is highly expressed in ovary

Mutations in CTSD play a causal role in neuronal ceroid lipofuscinosis-10 and may be involved in the pathogenesis of several other diseases

This gene encodes a large protein that resides in the limiting membrane of endosomes and lysosomes and mediates intracellular cholesterol trafficking via binding of cholesterol to its N-terminal domain

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The alpha chain encoded by this gene is required for hippocampal long-term potentiation (LTP) and spatial learning

Human Semaphorin 6D, SEMA6D ELISA Kit, 96T Cell fragmentation and collection AVEN is highly expressed inShows growth cone collapsing activity on dorsal root ganglion (DRG) neurons in vitro. May be a stop signal for the DRG neurons in their target areas, and possibly also for other neurons. May also be involved in the maintenance and remodeling of neuronal connections.