IDI1 Rabbit Polyclonal Antibody, 20ul Liquid Handling Five alternatively spliced transcript variants

Five alternatively spliced transcript variants encoding distinct isoforms have been reported

Hyperphosphorylation of Rb proteins results in a loss of E2F binding and allows for transcriptional activation and cell cycle progression

Polypeptide 2 (heart/muscle isoform) of subunit VIa is encoded by a different gene

This gene is located in the cystatin locus and encodes an epididymal-specific protein shown to have antimicrobial activity against E

A related pseudogene is located near this gene

IDI1 Rabbit Polyclonal Antibody, 20ul Liquid Handling Five alternatively spliced transcript variantsIDI1 encodes a peroxisomally localized enzyme that catalyzes the interconversion of isopentenyl diphosphate (IPP) to its highly electrophilic isomer, dimethylallyl diphosphate (DMAPP), which are the substrates for the successive reaction that results in the synthesis of farnesyl diphosphate and, ultimately, cholesterol. It has been shown in peroxisomal deficiency diseases such as Zellweger syndrome and neonatal adrenoleukodystrophy that there is