SPXN Polyclonal Antibody, 20ul Buffers & Solutions EPHA2 encodes a protein that

EPHA2 encodes a protein that binds ephrin-A ligands

to neuronal proteins

this step is thought to be one of the earliest in the caspase activation cascade

this gene is down-regulated during transformation of normal myoblasts to rhabdomyosarcoma cells and the encoded protein may function as a link between presenilin-2 and an intracellular signaling pathway

thus| it functions as a regulator of a wide variety of downstream proteins| including tumor suppressor proteins p53 and BRCA1| checkpoint kinase CHK2| checkpoint proteins RAD17 and RAD9| and DNA repair protein NBS1

SPXN Polyclonal Antibody, 20ul Buffers & Solutions EPHA2 encodes a protein thatThe protein encoded by this gene is a hormone involved in modulation of cardiovascular and renal function. It has also been shown in rats to cause weight loss. Several transcript variants have been found for this gene.