UBP20 Rabbit Polyclonal Antibody, 20ul Pipette Controller compared to members 1-3

compared to members 1-3

Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation

sterilized by irradiationto SAL 10^-6

Annexin A1 inhibits phospholipase A2 and has anti-inflammatory activity

Three alternatively spliced transcript variants that encode different protein isoforms have been described

UBP20 Rabbit Polyclonal Antibody, 20ul Pipette Controller compared to members 1-3This gene encodes a ubiquitin specific processing protease that was first identified as a substrate of the VHL (von Hippel Lindau disease) protein E3 ubiquitin ligase complex. In addition to being ubiquitinated by the VHL E3 ligase complex this enzyme deubiquitinates hypoxia inducible factor (HIF) 1 alpha and thereby causes increased expression of HIF 1alpha targeted genes which play a role in angiogenesis glucose metabolism cell proliferation and