BIG2 Polyclonal Antibody, 100ul Purification Two alternatively spliced transcript variants

Two alternatively spliced transcript variants that encode different protein isoforms have been described for this gene

This protein forms a heterodimeric complex and binds and activates| in a glucose-dependent manner| carbohydrate response element (ChoRE) motifs in the promoters of triglyceride synthesis genes

The protein encoded by CLEC6A (C-type lectin domain family 6 member A) is a type II membrane receptor with an extracellular C-type lectin-like domain fold

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chromosome 2 encodes over 1

BIG2 Polyclonal Antibody, 100ul Purification Two alternatively spliced transcript variantsADP ribosylation factors (ARFs) play an important role in intracellular vesicular trafficking. The protein (ADP ribosylation factor guanine nucleotide exchange factor 2) encoded by ARFGEF2 is involved in the activation of ARFs by accelerating replacement of bound GDP with GTP and is involved in Golgi transport. It contains a Sec7 domain, which may be responsible for its guanine nucleotide exchange activity and also brefeldin A inhibition.