NIPA Polyclonal Antibody, 100ul Cryopreservation The encoded protein prefers glycoproteins

The encoded protein prefers glycoproteins rather than glycolipids as substrates and shows restricted substrate specificity| utilizing only the trisaccharide sequence Neu5Ac-alpha-2|3-Gal-beta-1|3-GalNAc

and G protein beta-gamma subunit

where it may contribute to insulin resistance in glucose uptake

Does not demethylate histone H3 'Lys-4'

Defects in this gene have been reported to be associated with protein alveolar proteinosis (PAP)

NIPA Polyclonal Antibody, 100ul Cryopreservation The encoded protein prefers glycoproteinsZC3HC1 encodes an F box containing protein that is a component of an SCF type E3 ubiquitin ligase complex that regulates the onset of cell division. The G2 M transition in the cell cycle requires the interaction of the proteins cyclin B1 and cyclin dependent kinase 1. The activated ubiquitin ligase complex targets the protein cyclin B1 for degradation, preventing this transition to mitosis.