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POT1 Polyclonal Antibody, 50ul Site-directed Mutagenesis The encoded protein binds directly

SKU: 46069668722

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POT1 Polyclonal Antibody, 50ul Site-directed Mutagenesis The encoded protein binds directlyPOT1 is a member of the telombin family and encodes a nuclear protein involved in telomere maintenance. Specifically, protection of telomeres 1 functions as a member of a multi protein complex that binds to the TTAGGG repeats of telomeres, regulating telomere length and protecting chromosome ends from illegitimate recombination, catastrophic chromosome instability, and abnormal chromosome segregation. Increased transcriptional expression of POT1 is

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Description

The encoded protein binds directly to retinoblastoma protein

The human HUNK gene localizes to chromosome 21q22 and encodes a protein with nucleocytoplasmic distribution and localizes to the centrosome

Leukotrienes are lipid mediators synthesized from arachidonic acid by lipoxygenase enzymes

a CGG-repeat expansion from 5-22 repeats to 68-450 repeats has been identified in the first intron of this gene

It heteromultimerizes with another MAGUK protein

POT1 Polyclonal Antibody, 50ul Site-directed Mutagenesis The encoded protein binds directlyPOT1 is a member of the telombin family and encodes a nuclear protein involved in telomere maintenance. Specifically, protection of telomeres 1 functions as a member of a multi protein complex that binds to the TTAGGG repeats of telomeres, regulating telomere length and protecting chromosome ends from illegitimate recombination, catastrophic chromosome instability, and abnormal chromosome segregation. Increased transcriptional expression of POT1 is

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