FBX46 Rabbit Polyclonal Antibody, 50ul Enzymes Increased expression of this gene

Increased expression of this gene in colorectal cancers compared to matched normal colonic mucosa has been observed

resulting in a decrease in sAPP-alpha production and increased amyloidogenic P3 peptide production

gamma chain (IL2RG)

EPH receptors typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats

This gene is a member of the SP100/SP140 family of nuclear body proteins and encodes a leukocyte-specific nuclear body component

FBX46 Rabbit Polyclonal Antibody, 50ul Enzymes Increased expression of this geneMembers of the F box protein family such as FBXO46 are characterized by an approximately 40 amino acid F box motif. SCF complexes formed by SKP1 (MIM 601434) cullin (see CUL1; MIM 603134) and F box proteins act as protein ubiquitin ligases. F box proteins interact with SKP1 through the F box and they interact with ubiquitination targets through other protein interaction domains (Jin et al. 2004