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Flt3-L Polyclonal Antibody, 50ul[BT-AP03284] Antibody Humanization Alternative splicing has been observed

SKU: 45831330598

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PLN162.00 PLN194.00

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Flt3-L Polyclonal Antibody, 50ul[BT-AP03284] Antibody Humanization Alternative splicing has been observedDendritic cells (DCs) provide the key link between innate and adaptive immunity by recognizing pathogens and priming pathogen specific immune responses. FLT3LG controls the development of DCs and is particularly important for plasmacytoid DCs and CD8 (see MIM 186910) positive classical DCs and their CD103 (ITGAE; MIM 604682) positive tissue counterparts (summary by Sathaliyawala et al. 2010 [PubMed: 20933441]).

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Description

Alternative splicing has been observed in this gene

Component of a mSin3A corepressor complex that contains SIN3A| SAP130| SUDS3/SAP45| ARID4B/SAP180| HDAC1 and HDAC2

Alternative splicing may result in several transcript variants| however

Like its somatic cell counterpart

The protein encoded by this gene is a member of the cyclin family of proteins

Flt3-L Polyclonal Antibody, 50ul[BT-AP03284] Antibody Humanization Alternative splicing has been observedDendritic cells (DCs) provide the key link between innate and adaptive immunity by recognizing pathogens and priming pathogen specific immune responses. FLT3LG controls the development of DCs and is particularly important for plasmacytoid DCs and CD8 (see MIM 186910) positive classical DCs and their CD103 (ITGAE; MIM 604682) positive tissue counterparts (summary by Sathaliyawala et al. 2010 [PubMed: 20933441]).

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