MSPD3 Polyclonal Antibody, 50ul Sample Library Tubes Studies of the mouse counterpart

Studies of the mouse counterpart suggest that this gene may function as a testis specific transcription factor during spermatogenesis

The N-terminal region is required for nuclear localization and the C-terminal region mediates transcriptional activity

The protein encoded by this gene functions as a signal transducer during differentiation of myoblasts to myotubes

Required to control retinal neovascularization in adult ocular endothelial cells

The encoded protein contains an N-terminal calcium and phospholipid binding C2 domain followed by multiple tryptophan-rich WW domains and| a C-terminal HECT ubiquitin ligase catalytic domain

MSPD3 Polyclonal Antibody, 50ul Sample Library Tubes Studies of the mouse counterpartThis gene encodes a multi pass membrane protein with a major sperm protein (MSP) domain. The deletion of a similar mouse gene is associated with defective cardiac development and neonatal lethality. Alternate transcriptional splice variants, encoding different isoforms, have been described.