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Ob-R Polyclonal Antibody, 100ul[BT-AP06323] Endonucleases & Exonucleases It may play an important

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Ob-R Polyclonal Antibody, 100ul[BT-AP06323] Endonucleases & Exonucleases It may play an importantLeptin receptor encoded by LEPR belongs to the gp130 family of cytokine receptors that are known to stimulate gene transcription via activation of cytosolic STAT proteins. This protein is a receptor for leptin (an adipocyte specific hormone that regulates body weight), and is involved in the regulation of fat metabolism, as well as in a novel hematopoietic pathway that is required for normal lymphopoiesis. Mutations in this gene have been associated

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Description

It may play an important role in hemopoietic differentiation

Defects in this gene are a cause of polycystic kidney disease (PKD)

Important for the resorption of phosphate by the kidney

Probable G-protein coupled receptor 82 is a member of a family of proteins that contain seven transmembrane domains and transduce extracellular signals through heterotrimeric G proteins

This gene location is also the candidate region of two different neurologic diseases: early-onset parkinsonism (Waisman syndrome) and X-linked mental retardation (MRX3)

Ob-R Polyclonal Antibody, 100ul[BT-AP06323] Endonucleases & Exonucleases It may play an importantLeptin receptor encoded by LEPR belongs to the gp130 family of cytokine receptors that are known to stimulate gene transcription via activation of cytosolic STAT proteins. This protein is a receptor for leptin (an adipocyte specific hormone that regulates body weight), and is involved in the regulation of fat metabolism, as well as in a novel hematopoietic pathway that is required for normal lymphopoiesis. Mutations in this gene have been associated

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