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DNA pol Epsilon A Polyclonal Antibody, 50ul Hepatocytes cofactor:Binds 1 manganese ion per

SKU: 45621492590

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DNA pol Epsilon A Polyclonal Antibody, 50ul Hepatocytes cofactor:Binds 1 manganese ion perPOLE (DNA polymerase epsilon, catalytic subunit) encodes the catalytic subunit of DNA polymerase epsilon. The enzyme is involved in DNA repair and chromosomal DNA replication. Mutations in POLE have been associated with colorectal cancer 12 and facial dysmorphism, immunodeficiency, livedo, and short stature.

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Description

cofactor:Binds 1 manganese ion per subunit

This gene has abundant and specific expression in the kidney

The protein encoded by this gene belongs to the SMAD family of proteins

and is localized to vesicular structures and the plasma membrane

NUTF2 encodes a cytosolic factor that facilitates protein transport into the nucleus

DNA pol Epsilon A Polyclonal Antibody, 50ul Hepatocytes cofactor:Binds 1 manganese ion perPOLE (DNA polymerase epsilon, catalytic subunit) encodes the catalytic subunit of DNA polymerase epsilon. The enzyme is involved in DNA repair and chromosomal DNA replication. Mutations in POLE have been associated with colorectal cancer 12 and facial dysmorphism, immunodeficiency, livedo, and short stature.

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