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PDX-1 Polyclonal Antibody, 50ul Site-directed Mutagenesis A chromosomal translocation that includes

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PDX-1 Polyclonal Antibody, 50ul Site-directed Mutagenesis A chromosomal translocation that includesThe protein encoded by PDX1 is a transcriptional activator of several genes, including insulin, somatostatin, glucokinase, islet amyloid polypeptide, and glucose transporter type 2. The encoded nuclear protein is involved in the early development of the pancreas and plays a major role in glucose dependent regulation of insulin gene expression. Defects in this gene are a cause of pancreatic agenesis, which can lead to early onset insulin dependent

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Description

A chromosomal translocation that includes this gene is associated with Peters' anomaly

This gene encodes a member of the DNAJ protein family

Defects in VCL are the cause of cardiomyopathy dilated type 1W

a member of the RAS oncogene family

RAD51 encoded by RAD51(RAD51 recombinase) is a member of the RAD51 protein family

PDX-1 Polyclonal Antibody, 50ul Site-directed Mutagenesis A chromosomal translocation that includesThe protein encoded by PDX1 is a transcriptional activator of several genes, including insulin, somatostatin, glucokinase, islet amyloid polypeptide, and glucose transporter type 2. The encoded nuclear protein is involved in the early development of the pancreas and plays a major role in glucose dependent regulation of insulin gene expression. Defects in this gene are a cause of pancreatic agenesis, which can lead to early onset insulin dependent

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