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NPM(Phospho-Ser4) Rabbit Polyclonal Antibody, 20ul DNA Libraries Synthesis Four transcript variants encoding distinct

SKU: 45404211229

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NPM(Phospho-Ser4) Rabbit Polyclonal Antibody, 20ul DNA Libraries Synthesis Four transcript variants encoding distinctThis gene encodes a phosphoprotein which moves between the nucleus and the cytoplasm. The gene product is thought to be involved in several processes including regulation of the ARF p53 pathway. A number of genes are fusion partners have been characterized in particular the anaplastic lymphoma kinase gene on chromosome 2. Mutations in this gene are associated with acute myeloid leukemia. More than a dozen pseudogenes of this gene have been identified.

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Description

Four transcript variants encoding distinct isoforms have been identified for ALDH1A2

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Aldehyde dehydrogenase isozymes are thought to play a major role in the detoxification of aldehydes generated by alcohol metabolism and lipid peroxidation

Participates in Wnt signaling (By similarity)

and competes with E1A for binding sites in p300/CBP

NPM(Phospho-Ser4) Rabbit Polyclonal Antibody, 20ul DNA Libraries Synthesis Four transcript variants encoding distinctThis gene encodes a phosphoprotein which moves between the nucleus and the cytoplasm. The gene product is thought to be involved in several processes including regulation of the ARF p53 pathway. A number of genes are fusion partners have been characterized in particular the anaplastic lymphoma kinase gene on chromosome 2. Mutations in this gene are associated with acute myeloid leukemia. More than a dozen pseudogenes of this gene have been identified.

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