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Mdm2 Polyclonal Antibody, 100ul[BT-AP05302] Thermal Control AKT2 is a putative oncogene

SKU: 45112096518

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PLN141.00 PLN163.00

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Mdm2 Polyclonal Antibody, 100ul[BT-AP05302] Thermal Control AKT2 is a putative oncogeneMDM2 encodes a nuclear localized E3 ubiquitin ligase. E3 ubiquitin protein ligase Mdm2 can promote tumor formation by targeting tumor suppressor proteins, such as p53, for proteasomal degradation. MDM2 is itself transcriptionally regulated by p53. Overexpression or amplification of this locus is detected in a variety of different cancers. There is a pseudogene for this gene on chromosome 2. Alternative splicing results in a multitude of transcript

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Description

AKT2 is a putative oncogene encoding a protein belonging to a subfamily of serine/threonine kinases containing SH2-like (Src homology 2-like) domains

Binds to CXCR3

cytokine-induced SATA signaling

This gene encodes the poly(ADP-ribosyl)transferase 3

Keratin 15 encoded by KRT15 is a member of the keratin gene family

Mdm2 Polyclonal Antibody, 100ul[BT-AP05302] Thermal Control AKT2 is a putative oncogeneMDM2 encodes a nuclear localized E3 ubiquitin ligase. E3 ubiquitin protein ligase Mdm2 can promote tumor formation by targeting tumor suppressor proteins, such as p53, for proteasomal degradation. MDM2 is itself transcriptionally regulated by p53. Overexpression or amplification of this locus is detected in a variety of different cancers. There is a pseudogene for this gene on chromosome 2. Alternative splicing results in a multitude of transcript

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