CD57 Polyclonal Antibody, 50ul[BT-AP02083] Electronic Pipette Contains 3 EGF-like domains

Contains 3 EGF-like domains

is one of several HOXC genes located in a cluster on chromosome 12

The protein interacts with several other components of basement membranes

Mutations in this gene cause xeroderma pigmentosum complementation group G (XP-G)

and its expression and activation is associated with transformation and tumorigenesis

CD57 Polyclonal Antibody, 50ul[BT-AP02083] Electronic Pipette Contains 3 EGF-like domainsCOL4A2 encodes one of the six subunits of type IV collagen, the major structural component of basement membranes. The C terminal portion of the protein, known as canstatin, is an inhibitor of angiogenesis and tumor growth. Like the other members of the type IV collagen gene family, COL4A2 is organized in a head to head conformation with another type IV collagen gene so that each gene pair shares a common promoter.