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p57 Monoclonal Antibody, 100ul Plasma Both subunits are members of

SKU: 44201253659

4.6
EUR135.00 EUR180.00

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p57 Monoclonal Antibody, 100ul Plasma Both subunits are members ofThis gene is imprinted, with preferential expression of the maternal allele. The encoded protein is a tight binding, strong inhibitor of several G1 cyclin Cdk complexes and a negative regulator of cell proliferation. Mutations in this gene are implicated in sporadic cancers and Beckwith Wiedemann syndorome, suggesting that this gene is a tumor suppressor candidate. Three transcript variants encoding two different isoforms have been found for this gene.

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Description

Both subunits are members of the activator protein-1 superfamily of basic leucine zipper (bZIP) proteins (see MIM 165160)

this product does not include the standard SE4-100 (19400041)

The encoded protein localizes to the Golgi apparatus and may play a role in spermatogenesis

and gastrointestinal system

Mutations in STXBP1 have been associated with infantile epileptic encephalopathy-4

p57 Monoclonal Antibody, 100ul Plasma Both subunits are members ofThis gene is imprinted, with preferential expression of the maternal allele. The encoded protein is a tight binding, strong inhibitor of several G1 cyclin Cdk complexes and a negative regulator of cell proliferation. Mutations in this gene are implicated in sporadic cancers and Beckwith Wiedemann syndorome, suggesting that this gene is a tumor suppressor candidate. Three transcript variants encoding two different isoforms have been found for this gene.

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