Histone H4 (Tri Methyl Lys59) Polyclonal Antibody, 100ul Immune Cell Analysis Four alternatively spliced transcript variants

Four alternatively spliced transcript variants of MAPK14 encoding distinct isoforms have been reported

tissue specificity:Ubiquitously expressed

and it also acts as a tumor suppressor

This gene encodes a hematopoietic-specific transcription factor that induces high-level expression of adult beta-globin and other erythroid genes

whose members function in vesicle transport during protein secretion and endocytosis

Histone H4 (Tri Methyl Lys59) Polyclonal Antibody, 100ul Immune Cell Analysis Four alternatively spliced transcript variantsHistones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures.