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TTF-1 Polyclonal Antibody, 20ul Adenovirus Packaging A pseudogene corresponding to MRPL32

SKU: 43748979397

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TTF-1 Polyclonal Antibody, 20ul Adenovirus Packaging A pseudogene corresponding to MRPL32NKX2 1 (NK2 homeobox 1) encodes a protein initially identified as a thyroid specific transcription factor. The encoded protein binds to the thyroglobulin promoter and regulates the expression of thyroid specific genes but has also been shown to regulate the expression of genes involved in morphogenesis. Mutations and deletions in NKX2 1 are associated with benign hereditary chorea, choreoathetosis, congenital hypothyroidism, and neonatal respiratory

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Description

A pseudogene corresponding to MRPL32 is found on chromosome Xp

Several transcript variants encoding different isoforms have been found for RPS6KA4

Amplification of this gene and/or overexpression of its protein have been reported in numerous cancers

A pseudogene of this gene is found on chromosome 8

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TTF-1 Polyclonal Antibody, 20ul Adenovirus Packaging A pseudogene corresponding to MRPL32NKX2 1 (NK2 homeobox 1) encodes a protein initially identified as a thyroid specific transcription factor. The encoded protein binds to the thyroglobulin promoter and regulates the expression of thyroid specific genes but has also been shown to regulate the expression of genes involved in morphogenesis. Mutations and deletions in NKX2 1 are associated with benign hereditary chorea, choreoathetosis, congenital hypothyroidism, and neonatal respiratory

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