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ATRIP Polyclonal Antibody, 20ul[BT-AP00754] Monoclonal Antibodies Breast tumors are initially dependent

SKU: 43732462473

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ATRIP Polyclonal Antibody, 20ul[BT-AP00754] Monoclonal Antibodies Breast tumors are initially dependentATRIP (ATR interacting protein) encodes an essential component of the DNA damage checkpoint. The encoded protein binds to single stranded DNA coated with replication protein A. The protein also interacts with the ataxia telangiectasia and Rad3 related protein kinase, resulting in its accumulation at intranuclear foci induced by DNA damage. Multiple transcript variants encoding different isoforms have been found for ATRIP.

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Description

Breast tumors are initially dependent on estrogens for growth and progression and can be inhibited by anti-estrogens such as tamoxifen

The encoded protein is insulin-responsive

which contain alternative first exons that are spliced to the remaining common exons

and efficient pipetting of multiple samples

Several transcript variants encoding the same protein have been found for TNFAIP3

ATRIP Polyclonal Antibody, 20ul[BT-AP00754] Monoclonal Antibodies Breast tumors are initially dependentATRIP (ATR interacting protein) encodes an essential component of the DNA damage checkpoint. The encoded protein binds to single stranded DNA coated with replication protein A. The protein also interacts with the ataxia telangiectasia and Rad3 related protein kinase, resulting in its accumulation at intranuclear foci induced by DNA damage. Multiple transcript variants encoding different isoforms have been found for ATRIP.

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