PMS2/PMS2CL Polyclonal Antibody, 50ul Cell Screening and Imaging Defects in ferritin proteins are

Defects in ferritin proteins are associated with several neurodegenerative diseases

Defects in ARNTL have been linked to infertility

it is packaged into neurosecretory vesicles and transported axonally to the nerve endings in the neurohypophysis where it is either stored or secreted into the bloodstream

Present in T-cells but not B-cells (at protein level)

The encoded protein is thought to act as a regulator of breast cancer growth and progression by binding to a phosphorylated form of integrin beta4

PMS2/PMS2CL Polyclonal Antibody, 50ul Cell Screening and Imaging Defects in ferritin proteins areThe protein encoded by PMS2 (PMS1 homolog 2, mismatch repair system component) is a key component of the mismatch repair system that functions to correct DNA mismatches and small insertions and deletions that can occur during DNA replication and homologous recombination. This protein forms heterodimers with the gene product of the mutL homolog 1 (MLH1) gene to form the MutL alpha heterodimer. The MutL alpha heterodimer possesses an endonucleolytic