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Rb Polyclonal Antibody, 20ul[BT-AP07686] Liquid Handling &Storage Some members of this protein

SKU: 43664805198

4.0
PLN97.20 PLN145.20

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Rb Polyclonal Antibody, 20ul[BT-AP07686] Liquid Handling &Storage Some members of this proteinThe protein encoded by RB1 (RB transcriptional corepressor 1) is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in RB1 are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma.

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Description

Some members of this protein family may play a role in apoptosis

The protein belongs to the L14E family of ribosomal proteins

In spite of the structural and functional differences

MDM4 encodes a nuclear protein that contains a p53 binding domain at the N-terminus and a RING finger domain at the C-terminus

COL6A3 encodes the alpha-3 chain

Rb Polyclonal Antibody, 20ul[BT-AP07686] Liquid Handling &Storage Some members of this proteinThe protein encoded by RB1 (RB transcriptional corepressor 1) is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in RB1 are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma.

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